Yazar "Şener, Göksel" için listeleme
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Combination of exercise and caloric restriction ameliorates nearly complete deleterious effects of aging on cardiovascular hemodynamic and antioxidant system parameters
Macit, Çaǧlar; Üstündağ, Ünsal Veli; Eyüpoğlu, Ozan Emre; Dağdeviren-Çevik, Özge; Şener, Göksel (Marmara University, 2020)Aging is a progressive and catabolic process by cells of the body are broken down. Study scrutinized the effects of exercise and caloric restriction in cardiovascular hemodynamics and antioxidant system parameters. Rats ... -
The effects of calorie restriction and exercise on age-related alterations in corpus cavernosum
Macit, Çaǧlar; Üstündağ, Ünsal Veli; Dağdeviren, Özge C.; Olguner Mercanoǧlu, Güldem; Şener, Göksel (Frontiers Media S.A., 2020)Background Aging is an important risk factor for erectile dysfunction (ED). Both calorie restriction (CR) and physical exercise (PE) have been established as a non-medical method for the improvement of detrimental changes ... -
Effects of exercise and calorie restriction on brain and testis in natural aging model
Hakgüder, Umay; Üstündağ, Ünsal Veli; Tüzüner, Burçin Alev; Genç, Nevin; İpekçi, Hazal; Özçelik, Reyhan; Tunalı Akbay, Tuğba; Şener, Göksel; Yarat, Ayşen; Emekli Alturfan, Ebru (2021)The aim of our study was to examine the effects of exercise and calorie restriction on various tissue damage and antioxidant parameters in the brain and testis of rats in a natural aging model. For this purpose, male ... -
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
Karakaya Çimen, Fatma Bedia; Macit, Çağlar; Sivas, Güzin Göksun; Tunalı Akbay, Tuğba; Şener, Göksel; Ercan, Feriha (Istanbul University Press, 2023)Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ... -
Panax ginseng extract ameliorates methotrexate-induced multi-organ damage via the regulation of oxidative stress
Macit, Çağlar; Ede Pazarbaşı, Seren; Yılmaz Karaoğlu, Sümeyye; Tunali Akbay, Tuğba; Karakaya Çimen, Fatma Bedia; Ercan, Feriha; Şener, Göksel (Marmara University, 2023)Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and ... -
Protective effect of N-Acetyl-L-Cysteine (NAC) on endosulfan-induced liver and kidney toxicity in rats
Beceren, Ayfer; Şehirli, Ahmet Özer; Omurtag, Gülden Zehra; Arbak, Serap; Turan, Pınar; Şener, Göksel (E-Century Publishing Corp, 2017)Endosulfan-induced systemic toxicity arises from oxidative stress and glutathione depletion. This study aims to investigate the possible protective effect of N-acetyl-L-cysteine (NAC) against endosulfan-induced toxicity ... -
Protective effects of momordica charantia (Bitter Melon) against metho-trexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers, 2023)Background: Methotrexate is a cytotoxic chemotherapeutic agent that has severe side ef-fects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers Ltd., 2023)Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Sudan kaçınma stresi uygulanmış erkek sıçan mesanesinde oksitosin etkisi: Işık ve elektron mikroskobik inceleme
Ak, Esin; Çikler Dülger, Esra; Özer Şehirli, Ahmet; Tetik, Şermin; Pişiriciler, Rabia; Şener, Göksel; Çetinel, Şule (Marmara Üniversitesi, 2015)Çalışmamızda, erkek sıçanlara uygulanan bir interstisyel sistit modeli olarak kabul gören sudan kaçınma stresinin (SKS) mesane hasarı üzerine etkisi ve oksitosin hormonunun strese bağlı olarak gelişen interstisyel sistit ...